Please use this identifier to cite or link to this item:
http://hdl.handle.net/10071/31400| Author(s): | Bonnard, B. Rouot, J. Silva, C. J. |
| Date: | 2024 |
| Title: | Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome |
| Journal title: | Optimal Control Applications and Methods |
| Volume: | 45 |
| Number: | 2 |
| Pages: | 544 - 574 |
| Reference: | Bonnard, B., Rouot, J., & Silva, C. J. (2024). Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome. Optimal Control Applications and Methods, 45(2), 544-574. https://doi.org/10.1002/oca.3089 |
| ISSN: | 0143-2087 |
| DOI (Digital Object Identifier): | 10.1002/oca.3089 |
| Keywords: | Biomathematics and population dynamics Optimal control in the permanent case Sampled-data control |
| Abstract: | We introduce the theoretical framework from geometric optimal control for a control system modeled by the generalized Lotka–Volterra equation, motivated by restoring the gut microbiota infected by Clostridium difficile combining antibiotic treatment and fecal injection. We consider both permanent control and sampled-data control related to the medical protocols. |
| Peerreviewed: | yes |
| Access type: | Embargoed Access |
| Appears in Collections: | DM-RI - Artigos em revistas científicas internacionais com arbitragem científica |
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| File | Size | Format | |
|---|---|---|---|
| article_102813.pdf Restricted Access | 1,4 MB | Adobe PDF | View/Open Request a copy |
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