Please use this identifier to cite or link to this item:
Fernandes, L. F.
Ferreira, H. A.
|Title:||Sex differences in functional connectivity between resting state brain networks in autism spectrum disorder|
|DOI (Digital Object Identifier):||10.1007/s10803-021-05191-6|
Autism spectrum disorder
Independent component analysis
Functional magnetic resonance imaging
|Abstract:||Functional brain connectivity (FBC) has previously been examined in autism spectrum disorder (ASD) between-resting-state networks (RSNs) using a highly sensitive and reproducible hypothesis-free approach. However, results have been inconsistent and sex differences have only recently been taken into consideration using this approach. We estimated main effects of diagnosis and sex and a diagnosis by sex interaction on between-RSNs FBC in 83 ASD (40 females/43 males) and 85 typically developing controls (TC; 43 females/42 males). We found increased connectivity between the default mode (DM) and (a) the executive control networks in ASD (vs. TC); (b) the cerebellum networks in males (vs. females); and (c) female-specific altered connectivity involving visual, language and basal ganglia (BG) networks in ASD—in suggestive compatibility with ASD cognitive and neuroscientific theories.|
|Access type:||Open Access|
|Appears in Collections:||CIS-RI - Artigos em revistas científicas internacionais com arbitragem científica|
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